The Prime Hook National Wildlife Refuge is a sanctuary for migratory birds and lies along the western shore of Delaware Bay. The refuge contains a variety of habitats, including freshwater and salt marshes, woodlands, grasslands, ponds, and forested areas. It supports 267 species of birds and a variety of reptiles, amphibians, and mammals. This route follows Prime Hook Creek and winds through a chain of several ponds before reaching Wilson Pond and Goose Pond near Prime Hook Road.